Alpers Disease Treatment Market Size, Share, Growth Report 2030

Alpers Disease Treatment Market

Alpers Disease Treatment Market By Diagnosis (Molecular Genetic Testing, Laboratory Tests, Electroencephalography (EEG), and Others), By Treatment (Speech Therapy, Anticonvulsant Drugs, Occupational Therapy, Physical Therapy, and Others), By Demographic (Adolescent, Adult, Childhood, and Infancy), By Symptoms (Dementia, Headache, Seizures, Liver Dysfunction, Spasticity, Blindness, Cerebral Degeneration, and Others), and By Region - Global and Regional Industry Overview, Market Intelligence, Comprehensive Analysis, Historical Data, and Forecasts 2023 – 2030

Category: Healthcare Report Format : PDF Pages: 207 Report Code: ZMR-7225 Published Date: Jun-2023 Status : Published
Market Size in 2022 Market Forecast in 2030 CAGR (in %) Base Year
USD 1.33 billion USD 1.90 billion 4.57% 2022

Alpers Disease Treatment Market

Industry Prospective:

The global Alpers disease treatment market size was worth around USD 1.33 billion in 2022 and is predicted to grow to around USD 1.90 billion by 2030 with a compound annual growth rate (CAGR) of roughly 4.57% between 2023 and 2030. The report analyzes the global Alpers disease treatment market drivers, restraints/challenges, and the effect they have on the demands during the projection period. In addition, the report explores emerging opportunities in the Alpers disease treatment industry.

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Alpers Disease Treatment Market: Overview

Alpers disease is also known as Alpers-Huttenlocher syndrome. It is an extremely rare but progressive genetic disorder that directly impacts the central nervous system of the patient, particularly affecting brain function. The main characteristics of Alpers disease are the onset of frequent seizures, liver dysfunction, and developmental regression. Primarily, the medical condition is caused by mutations in the Deoxyribonucleic Acid (DNA) polymerase subunit gamma (POLG) gene. This gene is responsible for maintaining the stability and integrity of mitochondrial DNA. The importance of mitochondria is well-known in the scientific community. They are structures within a cell that produce energy and a defect in the POLG gene can directly become the cause of the mitochondrial dysfunction. The disease onsets at the early stages of life and progresses through the life of the patient. Current treatments focus on managing the symptoms and providing supportive care. During the forecast period, the Alpers disease treatment industry is likely to witness steady growth.

Key Insights:

  • As per the analysis shared by our research analyst, the global Alpers disease treatment market is estimated to grow annually at a CAGR of around 4.57% over the forecast period (2023-2030)
  • In terms of revenue, the global Alpers disease treatment market size was valued at around USD 1.33 billion in 2022 and is projected to reach USD 1.90 billion, by 2030.
  • The Alpers disease treatment market is projected to grow at a significant rate due to the growing research and development
  • Based on diagnosis segmentation, molecular genetic testing was predicted to show maximum market share in the year 2022
  • Based on demographic segmentation, childhood was the leading demographic in 2022
  • On the basis of region, North America was the leading revenue generator in 2022

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Alpers Disease Treatment Market: Growth Drivers

Growing research and development to propel market growth

The global Alpers disease treatment market is projected to grow owing to the increasing investments toward higher research & development (R&D) in understanding more about the disease along with the innovation of new methods that can completely treat the condition. With such activities, the research community intends to learn more about the underlying reasons for mutation in the POLG genes which directly impacts the development of effective treatments and medicines. A 2023 report generated by Statista claims that Moderna, a leading pharmaceutical and biotechnology company, spent nearly USD 3.3 billion on R&D for several investigation and examination purposes. Moreover, the world, in recent times, has registered increased healthcare spending. People are getting better equipped with managing financial strains caused by medical emergencies which have further resulted in increased market growth.

Alpers Disease Treatment Market: Restraints

Limited understanding to restrict market expansion

The global Alpers disease treatment industry is expected to come across certain growth restrictions during the forecast period. One of the primary limitations which is also the most crucial one is the lack of thorough understanding of Alpers disease. Despite increased medical research in terms of theoretical knowledge and development of medical devices, the research community has been unable to breakthrough discoveries in terms of actual reasons and effective treatment of the condition.

Alpers Disease Treatment Market: Opportunities

Growing advancement in genetic research to provide excellent growth opportunities

The global Alpers disease treatment market may come across several growth opportunities during the forecast period owing to the increasing research on genetic studies. Over the years, several medical cases have been detected that are linked to genetic mutations. Some of these conditions cannot be resolved even with the aid of the most advanced medical tools. However, the recent US-based brain operation conducted on a fetus is an exemplary move in terms of the level of the growth trajectory that global medicine has achieved. The rise in interest and research in genetic study is one of the primary ways the medical community can develop an effective cure.

Alpers Disease Treatment Market: Challenges

High cost of treatment to challenge market growth

Since Alpers disease is a rare genetic disorder, the cost of treating the condition is high. This is due to the limited availability of resources which includes medicines as well as experts who deal with the condition. In underdeveloped economies that are already struggling with slow economic growth with the added burden of social-political unrest, the cost of treatment can be unaffordable. This is a challenge that Alpers disease treatment industry leaders need to overcome since access to quality medical care is a right of every patient.

Alpers Disease Treatment Market: Segmentation

The global Alpers disease treatment market is segmented based on diagnosis, treatment, demographic, symptoms, and region.

Based on diagnosis, the global market segments are molecular genetic testing, laboratory tests, electroencephalography (EEG), and others. In 2022, the industry witnessed the highest growth in the molecular genetic testing segment since this method involves the analysis of an individual's DNA to detect specific mutations such as that of the POLG gene, which is the primary reason for Alpers disease. This can be done using several techniques such as DNA sequencing or targeted gene panels. EEG methodology features the use of the electrical activity of the brain that detects abnormal brain wave patterns, such as epileptic discharges or slowing which is most associated with Alpers disease. The National Institute of Health (NIH) suggests that the condition impacts 1 in 100,000 people.

Based on treatment, the Alpers disease treatment industry divisions are speech therapy, anticonvulsant drugs, occupational therapy, physical therapy, and others.

Based on demographic, the global market segments are adolescent, adult, childhood, and infancy. The condition typically manifests in the age group of 1 to 4 years old and hence children are most vulnerable to the condition. However, it can occur to any person from age groups including adults. Infants are less likely to suffer from Alpers. Some of the early signs of Alpers disease include difficult-to-control seizures, loss of cognitive ability such as dementia, involuntary jerking of muscles which is also known as myoclonus, abnormal increase in muscle tone or stiffness or spasticity, and infection-associated encephalopathy which alters the way brain functions.

Based on symptoms, the Alpers disease treatment industry is divided into dementia, headache, seizures, liver dysfunction, spasticity, blindness, cerebral degeneration, and others.

Recent Developments:

  • In March 2023, Insmed Incorporated, a leading giant that deals in biopharmaceuticals to change the lives of people with rare medical diseases, announced developments that the company has been able to make in its well-funded early-stage research programs. The company plans to dive deeper into the analysis at its investor and analyst event called The Future of Rare at Insmed: Functional Genes, AI-Enhanced Proteins, Glowing Algae, and More
  • In December 2021, Pfizer, one of the world’s most prominent pharmaceutical companies, announced the opening of its new complex based out of Durham. Pfizer intends to invest higher in gene therapy mainly drawn by the potential of this segment in biotechnology. The site is 85,000 square feet and is part of a USD 800 million investment directed toward building 3 gene therapy units in the state of North Carolina

Alpers Disease Treatment Market: Report Scope

Report Attributes Report Details
Report Name Alpers Disease Treatment Market Research Report
Market Size in 2022 USD 1.33 Billion
Market Forecast in 2030 USD 1.90 Billion
Growth Rate CAGR of 4.57%
Number of Pages 207
Key Companies Covered Roche Holdings AG, Pfizer Inc., Novartis International AG, Sanofi S.A., Merck & Co., Inc., Biogen Inc., Moderna, Inc., Vertex Pharmaceuticals Incorporated, Alexion Pharmaceuticals, Inc., Takeda Pharmaceutical Company Limited, AbbVie Inc., Regeneron Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., Sarepta Therapeutics, Inc., BioMarin Pharmaceutical Inc., Genzyme Corporation (a subsidiary of Sanofi), Horizon Therapeutics plc, Ultragenyx Pharmaceutical Inc., Amicus Therapeutics, Inc., CRISPR Therapeutics AG, Agios Pharmaceuticals, Inc., Mitobridge (a subsidiary of Astellas Pharma Inc.), Stealth BioTherapeutics Corp., NeuroVive Pharmaceutical AB, and Epizyme, Inc.
Segments Covered By Diagnosis, By Treatment, By Demographic, By Symptoms, and By Region
Regions Covered North America, Europe, Asia Pacific (APAC), Latin America, Middle East, and Africa (MEA)
Base Year 2022
Historical Year 2017 to 2021
Forecast Year 2023 - 2030
Customization Scope Avail customized purchase options to meet your exact research needs. Request For Customization

Alpers Disease Treatment Market: Regional Analysis

North America to witness the highest growth

The global Alpers disease treatment market is projected to witness the highest growth in North America mainly driven by the presence of robust medical research facilities aided by the strength of research experts. The US is home to some of the world’s most dominant pharmaceutical companies that, in recent times, have increased their spending on research. This trend is specially registered after Covid-19. Furthermore, these companies receive tremendous support from the regional government which insists on maintaining its position as the country with the world’s most advanced healthcare infrastructure. Furthermore, higher awareness amongst medical practitioners along with access to advanced medical tools and diagnostic systems has helped North America assert its dominance in the global market. In Europe, the increasing healthcare expenditure could contribute to regional market expansion.

Alpers Disease Treatment Market: Competitive Analysis

The global Alpers disease treatment market is led by players like:

  • Roche Holdings AG
  • Pfizer Inc.
  • Novartis International AG
  • Sanofi S.A.
  • Merck & Co.Inc.
  • Biogen Inc.
  • Moderna Inc.
  • Vertex Pharmaceuticals Incorporated
  • Alexion Pharmaceuticals Inc.
  • Takeda Pharmaceutical Company Limited
  • AbbVie Inc.
  • Regeneron Pharmaceuticals Inc.
  • Ionis Pharmaceuticals Inc.
  • Sarepta Therapeutics Inc.
  • BioMarin Pharmaceutical Inc.
  • Genzyme Corporation (a subsidiary of Sanofi)
  • Horizon Therapeutics plc
  • Ultragenyx Pharmaceutical Inc.
  • Amicus Therapeutics Inc.
  • CRISPR Therapeutics AG
  • Agios Pharmaceuticals Inc.
  • Mitobridge (a subsidiary of Astellas Pharma Inc.)
  • Stealth BioTherapeutics Corp.
  • NeuroVive Pharmaceutical AB
  • Epizyme Inc.

The global Alpers disease treatment market is segmented as follows:

By Diagnosis

  • Molecular Genetic Testing
  • Laboratory Tests
  • Electroencephalography (EEG)
  • Others

By Treatment

  • Speech Therapy
  • Anticonvulsant Drugs
  • Occupational Therapy
  • Physical Therapy
  • Others

By Demographic

  • Adolescent
  • Adult
  • Childhood
  • Infancy

By Symptoms

  • Dementia
  • Headache
  • Seizures
  • Liver Dysfunction
  • Spasticity
  • Blindness
  • Cerebral Degeneration
  • Others

By Region

  • North America
    • The U.S.
    • Canada
  • Europe
    • France
    • The UK
    • Spain
    • Germany
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Southeast Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of The Middle East & Africa

Table Of Content

Methodology

FrequentlyAsked Questions

Alpers disease is also known as Alpers-Huttenlocher syndrome. It is an extremely rare but progressive genetic disorder that directly impacts the central nervous system of the patient, particularly affecting brain function.

The global Alpers disease treatment market is projected to grow owing to the increasing investments toward higher research & development (R&D) in understanding more about the disease along with the innovation of new methods that can completely treat the condition.

According to study, the global Alpers disease treatment market size was worth around USD 1.33 billion in 2022 and is predicted to grow to around USD 1.90 billion by 2030.

The CAGR value of the Alpers disease treatment market is expected to be around 4.57% during 2023-2030.

The global Alpers disease treatment market is projected to witness the highest growth in North America mainly driven by the presence of robust medical research facilities aided by the strength of research experts.

The global Alpers disease treatment market is led by players like Roche Holdings AG, Pfizer Inc., Novartis International AG, Sanofi S.A., Merck & Co., Inc., Biogen Inc., Moderna, Inc., Vertex Pharmaceuticals Incorporated, Alexion Pharmaceuticals, Inc., Takeda Pharmaceutical Company Limited, AbbVie Inc., Regeneron Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., Sarepta Therapeutics, Inc., BioMarin Pharmaceutical Inc., Genzyme Corporation (a subsidiary of Sanofi), Horizon Therapeutics plc, Ultragenyx Pharmaceutical Inc., Amicus Therapeutics, Inc., CRISPR Therapeutics AG, Agios Pharmaceuticals, Inc., Mitobridge (a subsidiary of Astellas Pharma Inc.), Stealth BioTherapeutics Corp., NeuroVive Pharmaceutical AB, and Epizyme, Inc.

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