Organ-on-chip is a 3D microfluidic cell structure chip that simulates a particular organ in the body along with its mechanics and physiological reactions using the computer chip manufacturing method, to execute procedures like breathing, peristalsis, and curing infections. The organ-on-chip plays an important role in the fields of drug discovery and research, as it assists in achieving greater precision in toxicity identification and testing to decrease the chances of drug failure in human clinical trials. In addition, traditional animal models were not guaranteed to correctly imitate human pathophysiology. The organ chip consists of a flexible polymer of the size of the computer memory stick, which has hollow microfluid channels for the cells of a particular human organ that is surrounded by the organ-specific physical microenvironment.
The increasing issues related to one’s health and rising demand for organ culture instruments based on lung and kidney are driving the organ-on-chip market worldwide. In addition, increasing projects by prominent chip organ implementation organizations will further contribute to the organ-on-chip market globally. For example, in 2017, the Netherlands Scientific Research Organization (NWO) discussed its plans for the country’s organ-on-chip initiative that focused on advances and growth of the same. However, the imitation of the extremely complicated architecture of human organs may limit the organ-on-chip market over the forecast time period. The Asia Pacific region's flourishing healthcare sector and China's elevated median age, which is one of Asia Pacific's most important markets, will further fuel the development of the worldwide organ-on-chip market in the years ahead.
The organ-on-chip market is fragmented based on product, application, and end-user. Based on product, the organ-on-chip market is classified into kidney-on-chip, lung-on-chip, heart-on-chip, liver-on-chip, and others. The application segment of the organ-on-chip market includes toxicology research, drug discovery, and others. The drug discovery segment is anticipated to dominate the organ-on-chip market in the years ahead. The end-user segment is divided into cosmetic industry, healthcare, and others. The healthcare sector will hold a major share of the market for organ-on-chip globally in the future.
North America will hold a major share of the organ-on-chip market globally, owing to rapid technological advances in the region. The Asia Pacific organ-on-chip market will witness a substantial growth rate in the organ-on-chip market over the forecast time period, due to the region's elevated population base and the flourishing healthcare industry.
Some key players of the organ-on-chip market are Emulate, AxoSim Technologies, CN Bio Innovations, Hurel Corporation, Ascendance Biotechnology, InSphero, Mimetas, Nortis, Organovo Holdings, and Tara Biosystems.
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