Global Phocomelia Market To Deliver High Revenue In North America

04-Jul-2023 | Zion Market Research

The global phocomelia market size was worth around USD 142.38 million in 2022 and is predicted to grow to around USD 219.51 million by 2030 with a compound annual growth rate (CAGR) of roughly 5.56% between 2023 and 2030.

Global Phocomelia Market Size

Phocomelia is a rare birth defect or a congenital condition that causes underdevelopment or absence of limbs and in particular the legs & arms. The phocomelia industry deals with the economic aspects related to products, treatments, and services used in the treatment of phocomelia. It encompasses various medical and healthcare products or services that address the medical need and mental well-being of patients affected by this condition. The condition is generally caused by exposure to certain chemicals or substances during pregnancy, specifically thalidomide. It was a medication that was generally given to pregnant women in the 1950s and 1960s. However, it was later discovered that thalidomide is a teratogen which means it causes birth defects if the developing fetus is exposed to it.

This review is based on a report by Zion Market Research, titled "Phocomelia Market By Causes (Alcohol Or Cocaine, Maternal Intake Of Thalidomide, Blood Flow Problems, Gestational Diabetes, And X-Ray Radiation), By Symptoms (Mental Deficiencies, Shortened Or Missing Limbs, Malformation Of The Uterus, Urethra, Kidney, Or Heart, Shorter Neck Length, Problems With Blood Clotting, Migraines, And Vomiting), By Mutations (Spontaneous Genetic Mutations And Inherited Mutations), By Treatment (Therapy, Prosthetics, And Surgery), And By Region - Global And Regional Industry Overview, Market Intelligence, Comprehensive Analysis, Historical Data, And Forecasts 2023 – 2030"- Report at

The global phocomelia market is projected to grow due to the rising awareness, diagnosis, and acceptance rate of the condition. As general public awareness of the disease has increased due to efforts undertaken by the international medical research community to understand the underlying causes of the condition, it has become possible to detect the condition during its early stages. This means the medical intervention processes are not delayed and timely procedures are likely to have better results. Moreover, the development or innovation of advanced screening techniques during pregnancy has allowed would-be parents to be better aware of any medical condition that may be affecting proper fetus development. This allows them to be better prepared for the future.

One of the crucial factors that have resulted in higher growth in the phocomelia industry is the acceptance of prosthetic procedures aided by the introduction of highly advanced customized prosthetic solutions that cater to the unique medical needs of every patient. Ongoing research into the causes, treatment options, and genetic aspects of phocomelia may help the medical community develop novel therapeutic approaches which may also help in eliminating all possible reasons that cause the condition.

The phocomelia industry is expected to come across certain growth restrictions due to the high associated cost of treatment. Prosthetic limbs, assistive devices, and rehabilitation therapies can be expensive. For instance, the average cost of a functional bionic prosthetic arm is between USD 20,000 to USD 80,000. Additionally, the impact of phocomelia on mental health remains a crucial point of discussion in the medical community. Coping with the challenges of living with a limb difference may lead to mental health issues such as anxiety, depression, or low self-esteem

The research and development for understanding the underlying genetic causes of the disease may provide growth opportunities while the lack of accessibility to advanced medical care could pose a challenge to further market expansion.

The global phocomelia market is segmented based on causes, symptoms, mutations, treatment, and region,

Based on causes, the global market segments are alcohol or cocaine, maternal intake of thalidomide, blood flow problems, gestational diabetes, and X-ray radiation.

Based on symptoms, the global market is divided into mental deficiencies, shortened or missing limbs, malformation of the uterus, urethra, kidney, or heart, shorter neck length, problems with blood clotting, migraines, and vomiting. The most common symptom of the condition is shortened or missing limbs. The hallmark feature of phocomelia is known to be limb malformation; however, it is sometimes also associated with other forms of medical conditions or malformations. Each case of phocomelia is specific in terms of the exact issue and associated medical concerns. Only certified medical professionals can conduct an accurate diagnosis of the disease and suggest treatment plans. Depending on the unique situation of the patient, they can recommend ideal therapy or treatment. As per NIH, in 2017, more than 57.7 million people were known to be living with limb amputation for segmented reasons.

Based on mutations, the phocomelia industry is divided into spontaneous genetic mutations and inherited mutations.

Based on treatment, the global market is divided into therapy, prosthetics, and surgery. The highest growth was observed in the therapy segment. It aims to improve strength, range of motion, and functional abilities of the remaining limbs which helps a person gain more confidence in the absence of a particular limb. Therapy is known to maximize the potential of people with this condition. Prosthetics are also registering a higher growth rate as there are growing advancements allowing access to customized prosthetics depending on patient requirements and medical needs. The use of lightweight materials and advanced designs have significantly improved the functionality and comfort of prosthetic limbs. In 2022, nearly 129 patients received prosthetic treatment at the All India Institute of Medical Sciences (AIIMS), Delhi healthcare facility.

The global phocomelia market is projected to register the highest growth in North America and it will be driven by crucial factors such as a better awareness rate of several aspects of phocomelia including causes and treatments. The availability of specialized medical services and favorable reimbursement policies along with growing research activities may contribute to higher regional expansion.

Europe has a significant market for phocomelia treatments led by the region's well-established healthcare systems, strong emphasis on research and development, and robust regulatory frameworks. Higher acceptance of the condition and a proactive approach to detecting phocomelia in the early stages of pregnancy could drive regional market revenue.

The Asia-Pacific market is expected to witness a high growth rate due to the presence of a large population base and increasing investment in the development of advanced prosthetics. Rising awareness and better access to medical services can drive market growth in countries like China, India, and Japan.

Recent Developments:

  • In May 2023, the University of Arkansas for Medical Sciences completed prosthetic implant surgery on the first Arkansan. The prosthetic was developed by Institute for Integrative and Innovative Research and is highly advanced in terms of restoring the sense of touch and grip force
  • In July 2022, researchers at the University of Oxford developed a new breath-driven concept that will change the way hand prosthetics are accessed. The new device is a substitute for Bowden cable-driven body-powered prosthetics

Phocomelia Market: Competitive Analysis

The global phocomelia market is led by players like:

  • Teva Pharmaceutical Industries Ltd.
  • Smaart Pharmaceuticals
  • Tiefenbacher API + Ingredients GmbH & Co. KG
  • Cambrex Corporation
  • Hangzhou Jinlan Pharmaceutical Technology Development Co. Ltd.
  • Emcure Pharmaceuticals
  • Össur
  • Hanger Clinic
  • Ottobock
  • Fillauer LLC
  • WillowWood
  • Blatchford Group
  • Endolite
  • Freedom Innovations
  • College Park Industries
  • Touch Bionics.

The global phocomelia market is segmented as follows:

By Causes

  • Alcohol or Cocaine
  • Maternal Intake of Thalidomide
  • Blood Flow Problems
  • Gestational Diabetes
  • X-Ray Radiation

By Symptoms

  • Mental Deficiencies
  • Shortened or Missing Limbs
  • Malformation of the Uterus, Urethra, Kidney, or Heart
  • Shorter Neck Length
  • Problems with Blood Clotting
  • Migraines
  • Vomiting

By Mutations

  • Spontaneous Genetic Mutations
  • Inherited Mutations

By Treatment

  • Therapy
  • Prosthetics
  • Surgery

By Region

  • North America
    • The U.S.
    • Canada
  • Europe
    • France 
    • The UK
    • Spain
    • Germany
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Southeast Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of Middle East & Africa

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