Global Extreme Lateral Interbody Fusion (XLIF) Surgery Market To Register Steady CAGR of 4.52% During The Forecast Period

06-Jul-2023 | Zion Market Research

The global extreme lateral interbody fusion (XLIF) surgery market size was worth around USD 982.39 million in 2022 and is predicted to grow to around USD 1398.67 million by 2030 with a compound annual growth rate (CAGR) of roughly 4.52% between 2023 and 2030.

Global Extreme Lateral Interbody Fusion (XLIF) Surgery Market Size

Extreme lateral interbody fusion (XLIF) surgery is a minimally invasive medical procedure that is conducted through the side of the body for the treatment of spinal disorders. XLIF has been a helpful procedure for reducing persistent leg and back pain even in patients that have not shown accurate responses to other treatments including pain medication, steroid injections, and physical therapy. In some cases, the procedure may require the use of implants such as rods and screws. The XLIF surgery industry is growing with the increasing number of spine-related surgeries conducted across the globe. In XLIF, the medical professional targets the space between spinal discs from the lateral side of the patient's body.

This review is based on a report by Zion Market Research, titled "Extreme Lateral Interbody Fusion (XLIF) Surgery Market By End-User (Spinal Surgery Centers, Hospitals, And Others), By Product Type (XLIF Interbody Fusion Systems And XLIF Interbody Cages), And By Region - Global And Regional Industry Overview, Market Intelligence, Comprehensive Analysis, Historical Data, And Forecasts 2023 – 2030"- Report at

The global extreme lateral interbody fusion (XLIF) surgery market is expected to grow due to increases due to the growing geriatric population. The chances of infection in XLIF procedures are relatively less when compared to other forms of spinal disorder treatment. XLIF is known to be a minimally invasive medical procedure, unlike other spine-related operational processes. In this method, doctors make smaller incisions that result in reduced blood loss, less postoperative pain, and faster recovery times. In addition to this, growing advancements in surgical technology and an increasing number of spinal injuries caused by accidents and other forms of trauma may result in a better growth trajectory. The extreme lateral interbody fusion surgery industry expansion especially concerns the innovation of better imaging technologies and the development of more advanced navigation systems, robotic-assisted surgery, and intraoperative imaging.

The lack of access to proper medical care could lead to reduced growth in the global extreme lateral interbody fusion surgery market. The Memon Healthcare Institute Hospital claims that nearly 50% of the Pakistani population does not have access to primary medical care. Moreover, factors such as limited application for severe cases and potential associated complications further impact XLIF surgery's reputation.

The growing investment toward technological advancement may provide growth opportunities while the existing competition from alternate methods of spine-related surgery may challenge market expansion.

The global extreme lateral interbody fusion (XLIF) surgery market is segmented based on end-user, product type, and region.

Based on end-user, the global market segments are spinal surgery centers, hospitals, and others. The highest growth was observed in the hospitals segment in 2022 especially centers with dedicated spine centers or departments. Most of the large hospitals are equipped with doctors, medical professionals, and diagnostic tools required to conduct every form of surgery. For instance, in March 2023, The spinal surgery centers are likely to witness higher growth due to growing efforts toward increasing investments. The regional governments along with private companies are working toward increasing investment and funding in such centers. Companion Spine proudly announced the addition of USD 5 million in funding bringing its Series A financing to a total of USD 60.1 million. The company has already received USD 55 million by February 2022. It is a spine pain-management company that mainly deals with the treatment of degenerative disc diseases (DDD) and lumbar spinal stenosis (LSS).

Based on product type, the extreme lateral interbody fusion surgery industry segments are XLIF interbody fusion systems and XLIF interbody cages. The demand for both product types is equally high. The former product type is a comprehensive set of instruments, implants, and accessories required for the XLIF surgical procedure. It includes specialized retractors, dilators, bone graft instruments, screws, rods, and other instruments. XLIF interbody cages, on the other hand, are implantable devices specifically designed for interbody fusion in XLIF surgeries. They are placed between adjacent vertebrae to restore disc height, decompress nerves, and facilitate fusion. These cages are considered the primary component of the procedure and hence are more commonly used. In 2018, NuVasive, Inc, a leading player in the market, introduced the XLIF® Lordotic Expandable (XLX) Interbody System after receiving 510(K) approval from the US FDA.

North America registered the highest growth in the global extreme lateral interbody fusion (XLIF) surgery market due to factors such as better access to healthcare, increasing innovation rate in terms of medical devices, and the presence of key medical device manufacturers. Asia-Pacific may generate significant revenue led by the rising investment by regional governments to encourage domestic healthcare infrastructure and increase patients with spinal cord issues. In 2021, over 30% of the Japanese population was over the age of 65 years, as per research. As per Mayo Clinic, their chances of spinal cord injury from a fall are higher after the age of 65 years.

Extreme Lateral Interbody Fusion (XLIF) Surgery Market: Competitive Analysis

The global extreme lateral interbody fusion (XLIF) surgery market is led by players like:

  • Medtronic plc
  • Johnson & Johnson
  • Stryker Corporation
  • Zimmer Biomet Holdings Inc.
  • NuVasive Inc.
  • Globus Medical Inc.
  • DePuy Synthes
  • B. Braun Melsungen AG
  • Alphatec Holdings Inc.
  • RTI Surgical Holdings Inc.
  • K2M Group Holdings Inc.
  • Orthofix Medical Inc.
  • Aesculap Implant Systems
  • SpineWave Inc.
  • MicroPort Scientific Corporation
  • Life Spine Inc.
  • Captiva Spine Inc.
  • CoreLink Surgical LLC
  • CTL Medical Corporation
  • Providence Medical Technology Inc.
  • Safe Orthopaedics
  • Spinal Elements Holdings Inc.
  • Spineology Inc.
  • Wenzel Spine Inc.
  • Xenco Medical.

The global extreme lateral interbody fusion (XLIF) surgery market is segmented as follows:

By End-User

  • Spinal Surgery Centers
  • Hospitals
  • Others

By Product Type

  • XLIF Interbody Fusion Systems
  • XLIF Interbody Cages

By Region

  • North America
    • The U.S.
    • Canada
  • Europe
    • France 
    • The UK
    • Spain
    • Germany
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Southeast Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of Middle East & Africa

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