The power of rat models and its advantages

15-May-2017 | Zion Market Research

For more than a period of 150 years, rats are used as models for studying and examining human diseases. Properties such as the size, physiological as well as cognitive characteristics, and different uses of rat models in cardio-biology, neurobiology, toxicology, and immunology study helps in propelling the growth of global rat models market.

Let us have a look as to why rats are preferred.

Metabolic Similarity

The metabolic composition of the rat is almost similar to humans as that in mice. This makes the rat a superior option when it comes to study pharmacokinetic as well as pharmacodynamic characteristics of the medicines and metabolic disorders of human beings.

Superior Behavior Modeling

The rat is the favored class for psychotherapeutic, modeling cognition, and neurological as well as affective disorders.

Physiological Similarity

Physiology of rat is better suitable for the examination of human cardiovascular disease, toxicology, as well as immunology.

Technical Advantages

The Bigger size of rats permits complicated operational manipulations. The capability to yield a larger volume of tissue and CSF/blood allows best experimental results.

Easier handling

Technicians and researchers operating with both rats and mice roughly unilaterally favor functioning with rats compared to mice. Rats rarely bite and are far more docile than mice. Mice are regularly portrayed as “erratic” and “skittish.” The elevated handling requirements of mice also make them stand behind when it comes to behavioral studies.

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Easier surgeries

The bigger size of the rat permits for operations that are much simpler to execute, and hence more preferred by people. Scientific training times are lowered with rat models lowering the period needed for data publication and acquisition. Simpler operations also mean less error, with elevated effectiveness and an additional savings of money, time, and life of the animal. Separate substructures can be more voluntarily targeted and studied, for instance, microinjection into tiny nuclei of the brain such as the curved nucleus of the hypothalamus is far simpler to execute in the rat.

In short, the rat models are always preferred due to the above factors and will always tend to power the development of the global rat models market in the coming future.

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