Global Upstream Bioprocessing Market Set For Rapid Growth, To Reach Around USD 10.81 Billion by 2025

18-Feb-2020 | Zion Market Research

Zion Market Research has published a new report titled “Upstream Bioprocessing Market by Product (Cell Culture Products, Bioreactors/Fermenters, Filters, Bags & Containers, Bioreactors Accessories and Others); by Workflow (Cell Culture, Media Preparation, and Cell Separation); by Mode (Outsourced and In-house): Global Industry Perspective, Comprehensive Analysis and Forecast, 2018 – 2025”. According to the report, global demand for upstream bioprocessing market was valued at approximately USD 4.58 billion in 2018, and is expected to generate revenue of around USD 10.81 billion by end of 2025, growing at a CAGR of around 13.2% between 2019 and 2025.

Browse the full “Upstream Bioprocessing Market by Product (Cell Culture Products, Bioreactors/Fermenters, Filters, Bags & Containers, Bioreactors Accessories and Others); by Workflow (Cell Culture, Media Preparation, and Cell Separation); by Mode (Outsourced and In-house): Global Industry Perspective, Comprehensive Analysis and Forecast, 2018 – 2025.” Report at

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Bioprocessing uses living cells such as plat cells, bacteria, animal cells or their components like enzymes, chloroplasts, etc. to obtain desired products. Bioprocess is primarily have two major processes namely upstream and downstream processing. The upstream bioprocessing deals with complete processing right from early cell separation/isolation and cultivation, to cell banking and cell culture expansion till final harvest.

Upstream bioprocessing market growth is fueled by various factors such as increasing research and development projects on biosimilars/biomolecules, monoclonal antibodies and small therapeutic peptide. Growing requirement for process optimization and safe, contamination free, and efficient production of biomolecules enhance the upstream bioprocessing market growth. Also, growing chronic disease burden worldwide is another key factor that is driving the upstream bioprocessing market growth. However, high cost of biomolecule production and processing may impede the market growth in the coming years. Collaborations among major players and institutes and increasing investments on research and development of novel therapeutic proteins may open new growth avenues in the upstream bioprocessing market.

The global upstream bioprocessing market is segmented based on mode, workflow, product, and region. Based on product, market is segmented into cell culture products, filters, bioreactors/fermenters, bioreactors accessories, bags & containers, and others. Market was dominated by bioreactors/fermenters segment in 2018 due to growing rate of installations by small and large scale production. Additionally, technological advancements and process automation for cost effective, safe and regulatory compliant manufacturing has attributed to bioreactors/fermenters segment growth. Highest growth is projected for cell culture products segment over the forecast period due to swelling demand for higher titer productivity cell cultures for monoclonal antibodies (mAbs) and biosimilars manufacturing.

Based on workflow, global upstream bioprocessing market is categorized into cell separation, media preparation, and cell culture. In 2018, cell culture workflow segment dominated the market with largest share and is projected to retain its dominance in the coming years. Technological advancements like micro-bioreactors based small scale bioproduction and use of data analysis & management solutions, bioinformatics tools is expected to attribute to the rapid growth of cell culture workflow segment.

Based on mode, market is categorized into outsourced and in-house. In-house mode was the leading segment in 2018 due to its cost-effectiveness and presence of large number of established in-house manufacturing firms.

At region level, North America was leading regional market for the global upstream bioprocessing market in 2018. Growing investment for R&D of mAbs and novel biomolecules, presence of major biopharmaceutical companies, presence of developed infrastructure and increasing chronic disease burden are key factors that boost the market growth in this region. In 2018, Europe was second leading regional market. The growth in Europe is supported by factors such as increasing collaborative research by biopharmaceutical players with academic and research institutes and increasing R&D activities on mAbs and biosimilar production. Over the forecast period, Asia Pacific is estimated to register fastest growth for upstream bioprocessing market due to growing number of market players concentrating on growth potential in emerging market.

Major players included in the report are Thermo Fisher Scientific, GE Healthcare, Sartorius AG, Merck KGaA, Applikon Biotechnology, Corning, Inc., Eppendorf AG, Lonza, PBS Biotech, Inc., Boehringer Ingelheim, Patheon, CellGenix GmbH, JM BIOCONNECT, Samsung BioLogics, Danaher Corporation and CMC Biologics.

The report segment of global upstream bioprocessing market as follows:

Global Upstream Bioprocessing Market: By Product

  • Bioreactors/Fermenters
  • Cell Culture Products
  • Filters
  • Bioreactors Accessories
  • Bags & Containers
  • Others

Global Upstream Bioprocessing Market: By Workflow

  • Media Preparation
  • Cell Culture
  • Cell Separation

Global Upstream Bioprocessing Market: By Mode

  • In-house
  • Outsourced

Global Upstream Bioprocessing Market: By Region

  • North America
    • The U.S.
    • Canada
  • Europe
    • France
    • The UK
    • Spain
    • Germany
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Southeast Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of Middle East & Africa

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