Global Acellular Therapy Market Is Predicted to Grow Around USD 32.61 Billion By 2030

14-Mar-2023 | Zion Market Research

Global Acellular Therapy Market Size Expected To Reach $32.61 Bn By 2030 | CAGR: 16.21%

The global acellular therapy market size was worth around USD 8.451 Billion in 2022 and is predicted to grow to around USD 32.61 Billion by 2030 with a compound annual growth rate (CAGR) of roughly 16.21% between 2023 and 2030.

Global Acellular Therapy Market Size

Acellular therapy includes medical treatments that are carried out using cell-derived products that do not contain living cells or are stripped of living cells. These products are home to extracellular matrix components, and bioactive molecules, along with other types of non-cellular products that can efficiently help in medical treatments or exhibit therapeutic impact. Acellular therapy makes use of the decellularization process which involves the removal of living cells from organs or tissues.

The final product left behind after the end of the process is a scaffold that is further put to use for regenerative medicine, tissue engineering, and other treatment processes. Some examples of acellular therapies include extracellular matrix (ECM) scaffolds. This process makes use of extracellular matrix powder to promote the healing process in the patient. The advanced medical treatment process has high potential and the medical community expects it to deliver tremendous results in the coming years since they have a high potential to deliver minimally invasive treatment.

The global acellular therapy market is projected to grow due to the increasing number of cases of chronic diseases that cannot be cured. Only precautions can be taken to ensure that the disease remains under control. These issues have led to the medical community struggling to find answers and acellular therapy has, until now, shown promising results in developing a cure for conditions like cancer. Furthermore, the growing demand for regenerative medicine could help the global industry garner higher revenue.

In this medical technique, the final goal is the restoration of damaged organs or tissues with the help of different types of engineering and biological approaches. Growth factor-based products and ECM scaffolds are of high importance in regenerative medicine. The increasing preference of patients and growing inclination toward minimally invasive treatment methods could cause more industry players to explore the advantages of acellular therapy. Constant development and advancements in tissue engineering and biotechnology could act as excellent growth propellers. Scholars have already started working on growth factor-replicating peptides, platelet-rich plasma, and other ways to improve the wound healing process.

However, the high cost of treatment using acellular methods is a major growth restraint. The techniques are expensive since it involves complex procedures along with advanced tools under the guidance of experts or specialists. The specific equipment needed for conducting acellular therapies is high in price. Furthermore, the treatment technique has shown limited efficacy thus raising questions on cost justification. This is especially observed in patients that are more complex in terms of health conditions. Other factors like safety concerns, regulatory challenges, and availability of alternative treatment plans could hamper the acellular therapy industry growth. 

The growing technological advancements could provide excellent growth opportunities while complex technicalities may challenge market propulsion

Global Acellular Therapy Market

The global acellular therapy market is segmented based on disease, application, scaffold, and region

Based on disease, the global market is divided into Parkinson, Alzheimer’s, chronic wounds, sclerosis, and cancer.

  • In 2022, the segment was dominated by the chronic wounds section since currently acellular therapies are most significantly used to treat conditions like venous leg ulcers, diabetic foot ulcers, and pressure ulcers
  • Chronic wounds are a major area of concern for the medical community as they affect billions of people across the world
  • These conditions are known to impact the quality of life of the patient since they have to live with it until the condition cures which can take many years
  • Almost 15% of diabetic patients are at risk of contracting diabetic foot ulcer

Based on application, the global market segments are hepatology, orthopedic, cardiology, neurology, oncology, and gastroenterology

  • In 2022, Orthopedic patients received the highest benefits from acellular therapy since the treatment method is used extensively to treat related cases
  • For instance, ECM scaffolds are used to treat musculoskeletal conditions like ligament, osteoarthritis, tendonitis, and other ligament injuries
  • Furthermore, acellular therapy is useful in wound care medicine
  • In the US, more than 25% of the adult population suffers from arthritis

Based on the scaffold, the global market is segmented into fused deposition modeling (FDM), cell-laden hydrogel, extracellular matrix (ECM), and selective laser sintering (SLS)

North America is anticipated to lead the global acellular therapy market with the US dominating the regional market. One of the key growth propellers is the high awareness rate amongst the medical community as well as the patient. Furthermore, a high standard of living and disposable income allows more people to opt for expensive medical treatments. Growth in Europe could be a result of increasing cases of chronic illnesses like cancer and diabetes and increasing preference toward regenerative medicine to tackle conditions that do not have a cure. Asia-Pacific is projected to be driven by the growing investments in the pharmaceutical industry, especially in China, India, and Singapore propelled by growing medical concerns.

This review is based on a report by Zion Market Research, titled Acellular Therapy Market By Disease (Parkinson’s, Alzeihmer’s, Chronic Wounds, Sclerosis, and Cancer), By Application (Hepatology, Orthopedic, Cardiology, Neurology, Oncology, and Gastroenterology), By Scaffold (Fused Deposition Modeling (FDM), Cell Laden Hydrogel, Extracellular Matrix (ECM), and Selective Laser Sintering (SLS), and By Region - Global and Regional Industry Overview, Market Intelligence, Comprehensive Analysis, Historical Data, and Forecasts 2022 – 2030.”- Report at

Recent Developments:

  • In Feb 2020, the US Food and Drugs Administration (FDA) approved the use of the INTEGRA Dermal Regeneration Template (DRT) developed by Integra LifeSciences. The device can be used for the treatment of diabetic foot ulcers that have reached a full thickness
  • In September 2020, Aziyo Biologics, a developer of regenerative tissue, filed for USD 58 million in Initial Public Offering (IPO)
  • In November 2020, Aziyo Biologics received a purchasing agreement from Premier Inc for the company’s Technology Breakthroughs Program

The global acellular therapy market is led by players like:

  • Codiak BioSciences Ltd.
  • Evox Therapeutics Ltd.
  • Stem Cell Medicine Ltd.
  • Capricor Therapeutics
  • Exogenous Therapeutics
  • Organicell Regenerative Medicine Inc.
  • Aegle Therapeutics Corp
  • ArunA Biomedical
  • Rion LLC.
  • Invitrx Therapeutics Inc.
  • Direct Biologics LLC.
  • Stem Cell Medicine Ltd.

The global acellular therapy market is segmented as follows:

By Disease

  • Parkinson’s
  • Alzheimer's
  • Chronic Wounds
  • Sclerosis
  • Cancer

By Application

  • Hepatology
  • Orthopedic
  • Cardiology
  • Neurology
  • Oncology
  • Gastroenterology

By Scaffold

  • Fused Deposition Modeling (FDM)
  • Cell Laden Hydrogel
  • Extracellular Matrix (ECM)
  • Selective Laser Sintering (SLS)

By Region

  • North America
    • The U.S.
    • Canada
  • Europe
    • France
    • The UK
    • Spain
    • Germany
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Southeast Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of Middle East & Africa

About Us:

Zion Market Research is an obligated company. We create futuristic, cutting-edge, informative reports ranging from industry reports, the company reports to country reports. We provide our clients not only with market statistics unveiled by avowed private publishers and public organizations but also with vogue and newest industry reports along with pre-eminent and niche company profiles. Our database of market research reports comprises a wide variety of reports from cardinal industries. Our database is been updated constantly in order to fulfill our clients with prompt and direct online access to our database. Keeping in mind the client’s needs, we have included expert insights on global industries, products, and market trends in this database. Last but not the least, we make it our duty to ensure the success of clients connected to us—after all—if you do well, a little of the light shines on us.

Contact Us:

Zion Market Research
244 Fifth Avenue, Suite N202
New York, 10001, United States
Tel: +49-322 210 92714
USA/Canada Toll-Free No.1-855-465-4651

Office Address

Contact Us

Zion Market Research
Tel: +1 (302) 444-0166
USA/Canada Toll Free No.+1 (855) 465-4651

Asia Pacific Office

3rd Floor, Mrunal Paradise, Opp Maharaja Hotel, Pimple Gurav, Pune 411061, Maharashtra, India
Phone No +91 7768 006 007, +91 7768 006 008

Contact #

US OFFICE NO +1 (302) 444-0166
US/CAN TOLL FREE +1 (855) 465-4651

We Are On Social

Industry Press Release

We Accept

We have secured system to process your transaction.

  • payment methods

Business Hours

Our support available to help you 24 hours a day, five days a week.

Monday - Friday: 9AM - 6PM

Saturday - Sunday: Closed