Global Superdisintegrants Market to Grow Around USD 0.71 Billion By 2030

03-Feb-2023 | Zion Market Research

The global superdisintegrants market size was worth around USD 380 Million in 2021 and is projected to grow around USD 700 Million by 2030, with a compounded annual growth rate (CAGR) of roughly 8.05% from 2022 to 2030.

Superdisintegrants refer to an amalgamation of substances that are added to drug formulations in order to ease the disintegration of tablet or capsule content into finer fragments. Superdisintegrating agents expedite the disintegration or swelling process of a tablet as soon as it comes in contact with a fluid. It can either be added before or after the initial wet granulation phase. Superdisintegrants have a set of distinctive properties such as remarkable molding, astounding hydration capacity, flow properties, and a considerable mouth feel. It is also compatible with other excipients that have equally beneficial tableting properties. There are numerous types of superdisintegrants in the market such as synthetic superdisintegrants, natural superdisintegrants, and others. These types of superdisintegrant are extensively used in several therapeutic areas such as neurology, oncology, gastrointestinal, cardiovascular, and hematology.

The demand in the global superdisintegrants market is expected to surge rapidly due to an increase in the adoption and popularity of orally disintegrating tablets (ODTs) in both nutraceutical and pharmaceutical industries. This is because more and more people across the globe are contracting and becoming vulnerable to numerous chronic and infectious diseases due to the adoption of a sedentary lifestyle and lack of physical exercise. In addition, an increase in the geriatric population and pediatric patients suffering from Alzheimer’s, cardiovascular, and neurological diseases significantly boost the use of both synthetic and natural superdisintegrants in the development of essential drugs in therapeutic areas. In addition, an increase in the expenditure and investment on research and development activities among various pharmaceutical and nutraceutical companies for the development of better and more efficient drugs for people create ample opportunities for the growth of the superdisintegrants industry. However, high costs associated with the treatment and diagnosis may restrict the growth of the market to an extent.

Global Superdisintegrants Market

The global superdisintegrants market is segmented based on product, formulation, therapeutic area, and region.

Based on formulation, the global market is bifurcated into tablets, capsules, and mouth-dissolving films. The tablets segment held the largest market share in 2021 and is further predicted to cite a promising CAGR during the forecast period. The huge share of this segment is mainly attributed to the extensive use of orally disintegrating tablets (ODTs) and fast-disintegrating tablets (FDTs) among healthcare providers and patients across the globe. This subsequently results in the expansive manufacturing of tablets by pharmaceutical manufacturers, thereby increasing the global demand. The striking demand for ODTs and FDTs is mainly due to their impeccable perks such as improved pre-gastric absorption, effortless swallowing among patients with dysphagia, enhanced drug bioavailability, and prolonged shelf-life. These factors exponentially bolster the growth of the segment during the forecast period.

Based on therapeutic area, the market is segregated into oncology, neurology, cardiology, infectious diseases. Among these, the neurological diseases segment held the dominating market share in 2021 and is further predicted to cite a significant CAGR during the forecast period. The major reason for the growth of this segment is growing incidences of neurological disorders among people, and thus orally disintegrating tablets are used widely as a treatment option for patients with neurological conditions. Superdisintegrants are extensively used in the production of ODTs for making antidepressant, antipsychotic, antimigraine, and sedative drugs. These factors drive the growth of the segment during the forecast period.

Geographically, in the global superdisintegrants market, the North America region held the largest market share in 2021 and is further expected to cite a significant CAGR during the forecast period. The major reason for the growth of the market include rising demand for generic drugs, availability of better healthcare infrastructure to undertake effective drug development procedures, rise in geriatric population, increase in cases of chronic disease, and growth in R&D expenditure by prominent pharmaceutical players in the region.

This review is based on a report by Zion Market Research, titled Superdisintegrants Market By Product (Croscarmellose Sodium, Crospovidone, Sodium Starch Glycolate, Ion Exchange Resins, Modified Cellulose, and Others), By Formulation (Tablet, Capsules, Mouth-Dissolving Film), By Therapeutic Area (Oncology, Neurology, Cardiology, Infectious Diseases), and By Region- Global and Regional Industry Overview, Market Intelligence, Comprehensive Analysis, Historical Data, and Forecasts 2022 – 2030.”- Report at

Recent Developments

  • In January 2022, DFE Pharma, a Germany-based innovative manufacturer of excipients, announced that they have added a new maize starch range in its Nutroféli excipients portfolio supplements in the rapidly evolving nutraceuticals industry. Nutraceutical products have gained massive traction in the past couple of years ever since the pandemic hit billions of people across the globe. Thus, consumers are incessantly becoming increasingly informed about self-care, well-being, and disease prevention. The German multinational company, with the launch of starches, envisions meeting the intrinsic needs of nutraceutical companies for superior quality, whilst ensuring timely delivery and supply. In addition, the maize starch portfolio gives enough options to companies to meet their formulation requirements as disintegrants, fillers, and binders, apart from other applications. This is mainly because starches essentially behave as diluents, disintegrants, and binders in most tablets and capsules, as an effective alternative to gelatine in soft gels, which makes it an utterly adaptable excipient.
  • In July 2021, Omya International AG, a dominant Switzerland-based supplier of minerals, announced the launch of its two new excipients, namely Omyanutra 300 DC and Omyanutra 300 Flash. The former notably facilitate free-flowing granules and enables the tablet to be compacted, while the latter comes with a superdisintegrant that is capable of expediting disintegration in oral and fast-dissolving tablets, irrespective of the rigidity of the solid dosage form. Both these products provide a much superior compactability when compared to standard excipients such as microcrystalline cellulose and lactose.

The global superdisintegrants market is dominated by player such as:

  • DFEPharma
  • Merck KGaA
  • Avantor Inc.
  • Corel PharmaChem
  • DuPont
  • Asahi Kasei Corporation
  • Dow
  • Ashland
  • RoquetteFreres

The global superdisintegrants market is segmented as follows:

By Product

  • Croscarmellose Sodium,
  • Crospovidone
  • Sodium Starch Glycolate
  • Ion Exchange Resins
  • Modified Cellulose
  • and Others

By Formulation

  • Tablet
  • Capsules
  • Mouth-Dissolving Film

By Therapeutic Area

  • Oncology
  • Neurology
  • Cardiology
  • Infectious Diseases

By Region

  • North America
    • The U.S.
    • Canada
  • Europe
    • France
    • The UK
    • Spain
    • Germany
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Southeast Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of Middle East & Africa

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