Global In Vivo Toxicology Testing Market Is Expected To Achieve Revenue Growth Of USD 7.54 Billion By 2028.

27-Jun-2022 | Zion Market Research

The global in-vivo toxicology market grasped a revenue growth of USD 5.23 billion in 2021 and is projected to grow to around USD 7.54 billion by 2028 at a CAGR rate of 6.3 percent over the forecast period. In vivo toxicology is the analysis of how chemicals affect living organisms other than humans. Before human exposure, it is crucial to have a thorough knowledge of the toxicological profiles of novel drug candidates from in vivo toxicology studies in order to make improvements to the current profiles of different medications, such as administration methods, formulations, and new indications. Drug cytotoxicity tests are performed to determine a drug's toxicity to living organisms. Initial in vivo toxicity studies aid in determining a drug's effects prior to first-in-human usage. Various animals, including rabbits, rodents, guinea pigs, and others, are used in in vivo toxicological investigations. The exposure methods include intramuscular, topical, intravenous, and others.

Numerous toxicological tests are now carried out using laboratory techniques because of the development of alternative approaches including in vitro and in silico toxicology testing. However, other tests, such as those for neurotoxicity, mutagenicity, developmental including teratogenicity in children & reproductive toxicity, and carcinogenicity are only performed in vivo. The use of animal models for in vivo toxicology testing is projected to increase as the emphasis on evaluating medications for carcinogenic toxicity increases. Drugs must also pass in vivo reproductive and developmental toxicity studies in order to move through regulatory processes. Market expansion is supported by these unique assays for in vivo investigations. In addition to this, R&D activities to find new vaccines and drugs have increased as a result of a growing need for innovative therapies. The need for in-vivo toxicity testing is growing as more clinical studies are conducted across the world. All these factors are fostering the growth of the in vivo toxicology testing market. However, restrictive practices and animal use for various reasons have been brought about by the implementation of laws and regulations for animal welfare and protection. Also, animals used in the cosmetic business have been outlawed in several nations during the last five years. These factors are restraining the growth of the market. On the other hand, the increasing use of humanized animal models for in vivo toxicology testing is likely to boost the market during the forecast period.

The development of the COVID-19 vaccine is receiving more attention, and this has created profitable chances for the growth of the in vivo toxicology testing market. Despite the potential the epidemic presents, there is now a restricted supply since animal model suppliers cannot keep up with the growing demand. The COVID-19 pandemic is anticipated to have a beneficial influence on the industry in the long run, nevertheless, as more firms enter this market to create novel solutions.

Global In Vivo Toxicology Testing Market

The global In-vivo toxicology in this research analysis is divided into product types, testing types, toxicity endpoints, testing facilities, end-user, and regions. The product types are classified as instruments, animal models, and reagents & kits. The testing types are divided into chronic toxicity testing, sub-chronic toxicity testing, sub-acute toxicity testing, and acute toxicity testing. The toxicity endpoints are immunotoxicity and systemic. The testing facilities are outsourced and in-house. End-users comprise academic institutes, research institutes, and CROs.

North America is expected to hold the maximum share in the global in vivo toxicology market during the forecast period. The North American market is primarily driven by the high demand for personalized medications. In addition to this, an increasing number of clinical trials and growing R&D activities for the development of novel & effective therapeutics are driving the market growth in this region. Over the projection period, Europe's market share for in-vivo toxicity testing will retain a sizable value. The rise of the industry will be fueled by the presence of several research organizations in the region. Additionally, the presence of major market participants in the region and an increase in clinical trials will fuel regional industry growth.

The key players in the global in-vivo toxicology market are Charles River Laboratories, The Jackson Laboratory, Envigo, Taconic Biosciences, Janvier Labs, Thermo Fisher Scientific, Danaher Corporation, Waters Corporation, Agilent Technologies, Shimadzu Corporation, Bruker Corporation, PerkinElmer, MerckkgaA, GE Healthcare, Bio-Rad laboratories, genOway, Cyagen Biosciences, GVK BIO, Polygene, Crown Biosciences, Transcure Bioservices, and Harbour BioMed.

Recent Developments:

  • In March 2020, GenOway acquired exclusive worldwide rights from Merck for its foundational CRISPR/Cas9 portfolio in the rodent field.
  • In July 2020, Taconic entered into an agreement with the University of Texas Medical Branch to distribute humanized ACE2 mice for COVID-19 research.
  • In December 2020, the Jackson Laboratory started the production of ACE2 mice to support the research on COVID-19.

Browse the full In Vitro Toxicology Testing Market By Technology (Proteomics, Toxicogenomics, High-Throughput Technologies, Transcriptomics, OMICS Technologies, Molecular Imaging Technologies, Metabolomics, Genomics, And Cell Culture Technology), By Product (Issue Culture Assays, Enzyme Toxicity Assays, Reagents & Labware, Cell-Based ELISA And Western Blots, Services, Bacterial Toxicity Assays, Assays Receptor Binding Assays, And Other Assays), By Industry (Oral Fluid Screening, Diagnostics, Chemical Industry, Hair Screening, Cosmetics & Household Products, Alcohol Screening, Pharmaceutical Industry, Food Industry, Urine Screening, And Other Diagnostics): Global Industry Perspective, Comprehensive Analysis And Forecast, 2020 – 2028. Report at https://www.zionmarketresearch.com/report/in-vitro-toxicology-testing-market

The global In Vitro Toxicology Testing market is segmented as follows:

By Technology

  • Proteomics
  • Toxicogenomics
  • High-throughput Technologies
  • Transcriptomics
  • OMICS Technologies
  • Molecular Imaging Technologies
  • Metabolomics
  • Genomics
  • Cell Culture Technology

By Product

  • Issue Culture Assays
  • Enzyme Toxicity Assays
  • Reagents & Labware
  • Cell-Based ELISA
  • Western Blots
  • Services
  • Bacterial Toxicity Assays
  • Receptor Binding Assays
  • Other Assays

By Industry

  • Oral Fluid Screening
  • Diagnostics
  • Chemical Industry
  • Hair Screening
  • Cosmetics & Household Products
  • Alcohol Screening
  • Pharmaceutical Industry
  • Food Industry
  • Urine Screening
  • Other Diagnostics

By Region

  • North America
    • The U.S.
    • Canada
  • Europe
    • France
    • The UK
    • Spain
    • Germany
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Southeast Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Rest of Middle East & Africa

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