The global tissue sealants and tissue adhesive market was worth around USD 1.5 billion in 2021 and is estimated to grow to about USD 2.9 billion by 2028, with a compound annual growth rate (CAGR) of approximately 8.6 percent over the forecast period.
Industry Prospective:
The global tissue sealants and tissue adhesive market was worth around USD 1.5 billion in 2021 and is estimated to grow to about USD 2.9 billion by 2028, with a compound annual growth rate (CAGR) of approximately 8.6 percent over the forecast period. The report analyzes the tissue sealants and tissue adhesive market’s drivers, restraints/challenges, and the effect they have on the demands during the projection period. In addition, the report explores emerging opportunities in the tissue sealants and tissue adhesive market.
Tissue Sealants and Tissue Adhesive Market: Overview
Sealants are materials used by surgeon to heal tissue that has been injured by a surgery or injury. Skin, internal organs, and blood vessels are among the tissues that have been damaged. Sealants are used in combination with mechanical procedures like sutures and staples to assist minimize blood loss and avoiding leaks. Tissue adhesives are liquid monomers that, when exposed to a moist surface (skin), begin an exothermic reaction, transforming into a polymer that establishes a strong tissue connection.
COVID-19 Impact:
The pandemic had an impact on how certain surgical operations were performed. For surgeons to continue to deliver safe and effective care to their patients throughout the COVID-19 outbreak, precise standards relevant to each specialty must be created and enforced. Due to regulatory authorities' strict guidance to avoid all non-emergent surgeries, the volume of surgeries has decreased dramatically during the pandemic, affecting the procuring of tissue sealants and tissue adhesives in surgical centers.
Tissue Sealants and Tissue Adhesive Market: Growth Drivers
Increase in number of orthopedic and cardiovascular procedures to foster the market
Over the forecast period, rising cardiovascular and orthopedic surgeries are expected to drive revenue growth in the global tissue sealants and tissue adhesive market. The ease of availability of novel tissue adhesives and tissue sealants among end users, combined with rising disposable money, is a major driver in the global increase in such procedures. Adhesives are essential in general surgery. Natural and manufactured polymeric materials can be used to create three-dimensional networks that adhere to target tissues chemically and physically, acting as adhesives, sealants, or hemostats. Because adhesives and sealants are such an important aspect of general surgery, demand for them will rise as the number of procedures performed increases. As a result, market growth is likely to be boosted.
Tissue Sealants and Tissue Adhesive Market: Restraints
Less market penetration for tissue sealants and adhesives in developing countries to hinder the growth
The market's growth is also likely to be hampered by the dearth of acceptance of tissue glue and bio-adhesive sealants in developing markets. This is due to a lack of knowledge about the advantages, cost-effectiveness, therapeutic application, and reliability of tissue adhesive and tissue sealants against alternative procedures or products, as well as tissue healing therapies.
Tissue Sealants and Tissue Adhesive Market: Opportunities
Technological advancement for product launches to create numerous opportunities for market growth
Companies have been working on the development of novel tissue glue and bio-adhesive sealants to reach a variety of consumers, including toddlers, young and elderly patients, during the last few years. Tissue sealants are currently used to protect sensitive, fragile, skin from damage, and to prevent cross-contamination & infection transmission. For innovative product launches, major companies are investing heavily in the R&D activities. All such factors are likely to generate numerous opportunities for the global tissues sealants and tissue adhesive market growth during the forecast period.
Tissue Sealants and Tissue Adhesive Market: Challenges
Limitations in the development of tissue adhesive to act as a major challenge for the market growth.
Despite the fact that many tissue adhesives form strong connections with tissue, they are frequently not designed for specific tissue applications. Tissue adhesives, in particular, do not biodegrade at a rate consistent with tissue repair, cause an unwanted inflammatory response upon adhesion or disintegration, fail to cohere in high-load-bearing applications, or do not match the characteristics of the underlying tissue. In the early stages of development, rigorous differentiation of target applications and greater in-depth investigation of tissue-surface features and tissue-environmental parameters are necessary. Despite the fact that the surface of the tissue and the surrounding environment change amongst tissues, the most typical technique is to utilize one type of adhesive for all conceivable tissues. This "one-size-fits-all" approach frequently results in tissue adhesive misuse, leading to inferior performance and dampening enthusiasm for potentially promising new materials. This could also lead to an incorrect cost-effectiveness analysis for specified unmet clinical requirements in the early stages of development, culminating in an exaggeration of cost in later stages of development and obstructing clinical translation. A failure to understand the physiological effects of adhesive materials after implantation is another factor for the research-to-product mismatch. All such limitations may pose challenge to the market growth.
Tissue Sealants and Tissue Adhesive Market: Segmentation
The global tissue sealants and tissue adhesive market is categorized based on product, application, end-user, and region. Based on the product, the market is divided into semi-synthetic & synthetic adhesives and biological or natural sealants. The application segment consists of neurosurgery, cosmetic surgery, cardiovascular surgery, gynecology surgery, orthopedic surgery, general surgery, and other applications. The end-user segment is bifurcated into ambulatory surgery centers, specialty clinics, and hospitals.
Report Scope:
Report Attribute | Details |
---|---|
Base Year | 2020 |
Historic Years | 2016 - 2020 |
Forecast Years | 2021 - 2028 |
Segments Covered | By Product Type, By Application, and By End Use |
Forecast Units | Value (USD Billion), and Volume (Units) |
Quantitative Units | Revenue in USD million/billion and CAGR from 2021 to 2028 |
Regions Covered | North America, Europe, Asia Pacific, Latin America, and Middle East & Africa, and Rest of World |
Countries Covered | U.S., Canada, Mexico, U.K., Germany, France, Italy, Spain, China, India, Japan, South Korea, Brazil, Argentina, GCC Countries, and South Africa, among others |
Number of Companies Covered | 10 companies with scope for including additional 15 companies upon request |
Report Coverage | Market growth drivers, restraints, opportunities, Porter’s five forces analysis, PEST analysis, value chain analysis, regulatory landscape, market attractiveness analysis by segments and region, company market share analysis, and COVID-19 impact analysis. |
Customization Scope | Avail customized purchase options to meet your exact research needs. |
Recent Developments
Tissue Sealants and Tissue Adhesive Market: Regional Landscape
North America to be the leader in the global market
Among the regions, North America is estimated to lead the global tissue sealants and tissue adhesive market during the forecast period. Because of its large population and technical advancements, North America accounted for the largest share of tissue sealants and tissue adhesive. However, market for tissue sealants and tissue adhesives is expected to expand significantly in Asia Pacific countries. Factors such as state-of-the-art medical research facilities and rising investments in healthcare infrastructure in this region, and also heightened understanding among both physicians & patients relating therapeutic approaches, enhanced life expectancy, and a rising population will push growing demands for tissue sealants and tissue adhesives in Asia Pacific region.
Tissue Sealants and Tissue Adhesive Market: Competitive Landscape
Integra LifeSciences, C.R Bard, Smith & Nephew, Exapharma, Johnson & Johnson, Baxter International Inc., Tissuemed Ltd., Chemence Medical, Inc., Cohera Medical, Inc., and Luna Innovations Incorporated are some of the predominant players that are operating in the global tissue sealants and tissue adhesive market.
Global tissue sealants and tissue adhesive market is segmented as follows:
By Product
By Application
By End-user
By Region
Secure skin closure is very basic and essential step in every surgical procedure. If the skin closure devices fail to provide the required strength and support to the skin tissue, there is a possibility that the wound edges can get separated, or it can offer a potential way for bacterial contamination. A promising alternative to the traditional closure techniques is tissue sealants and tissue adhesives. They form physically powerful bond crossways apposed wound boundaries and allow normal healing to occur below. Tissue sealants and adhesives save time in wound repair, provide a flexible water-resistant defensive coating and eradicate the need for suture removal. Some tissue glue examples are Cyanoacrylate, octyl cyanoacrylate (Dermabond), enbucrilate (Histoacryl), and N-butyl cyanoacrylate (Indermil, Liquiband).
According to the World Health Organization (WHO), about 1.25 million people across the globe die due to road accidents each year. About 20 to 50 million people undergo non-fatal injuries or suffer from disabilities. The growth of the tissue sealants and tissue adhesive market is mainly attributed to the rising need for managing blood loss in patients due to fatal accidental injuries. Other market driving factors include rising geriatric population, growth in the number of accidents, increasing incidence of trauma, and growing prevalence & incidence of various disorders such as obesity, diabetes, and cardiovascular diseases. Tissue sealants and tissue adhesives are extremely advanced medical devices and are commonly used in the healthcare sector. Rising number of surgeries lead to growing demand for wound closure devices and help in reducing post-operative infections and scars. In addition, FDA and CE mark approvals are also driving the global market. However, the cost associated with the products & wide clinical data necessities for introducing new products and lack of compensations for surgical sealants and adhesives can create restraints for the market. Improving healthcare infrastructure in developing markets is expected to fuel the growth of the tissue sealants and tissue adhesive market.
Based on product, tissue sealants and tissue adhesive market have been segmented into tissue sealants and tissue adhesives. Tissue sealant segment is further segmented into synthetic tissue sealants and non-synthetic tissue sealants. Non-synthetic tissue sealants segment is further divided into collagen-based tissue sealants, fibrin-based tissue sealants, and protein-based tissue sealants. Tissue adhesive segment is classified into Cyanoacrylate-based tissue adhesives and other cross-linkable polymer-based tissue adhesives. Based on end-user, tissue sealants and tissue adhesive market have been divided into specialty clinics, hospitals, and others. Based on application, tissue sealants and tissue adhesive market have been segmented into cardiovascular surgeries, laparoscopic surgeries, burns and skin grafting, general surgeries, cosmetic surgeries, and others.
Over the forecast period, North America is expected to remain the dominant region, owing to growing spending power of its population along with the availability of technologically advanced products. Asia Pacific region will witness the highest growth during the forecast period. This growth in the Asia Pacific market can be attributed to the rising geriatric population, the growing focus of key manufacturers in developing countries, speedy industrial growth, and rising demand for surgical interventions. Furthermore, the high adoption rate of advanced medical products along with the rising demand for quality healthcare activities in this region is supporting the market growth.
Some of the key players in tissue sealants and tissue adhesive market include Johnson & Johnson, Baxter International Inc., CryoLife, Inc., Exapharma Inc., Dentsply Sirona Inc., Smith & Nephew plc, C.R. Bard, Inc., Cohera Medical, Inc., Luna Innovations Incorporated, Integra LifeSciences Corporation, Tissuemed Ltd., B. Braun Melsungen AG, and Chemence Medical, Inc., among others.
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Over the forecast period, rising cardiovascular and orthopedic surgeries are expected to drive revenue growth in the global tissue sealants and tissue adhesive market. The ease of availability of novel tissue adhesives and tissue sealants among end users, combined with rising disposable money, is a major driver in the global increase in such procedures.
According to the Zion Market Research report, the global tissue sealants and tissue adhesive market was worth about 1.5 (USD billion) in 2021 and is predicted to grow to around 2.9 (USD billion) by 2028, with a compound annual growth rate (CAGR) of around 8.6 percent.
Among the regions, North America is estimated to lead the global tissue sealants and tissue adhesive market during the forecast period. Because of its large population and technical advancements, North America accounted for the largest share of tissue sealants and tissue adhesive.
Integra LifeSciences, C.R Bard, Smith & Nephew, Exapharma, Johnson & Johnson, Baxter International Inc., Tissuemed Ltd., Chemence Medical, Inc., Cohera Medical, Inc., and Luna Innovations Incorporated are some of the predominant players that are operating in the global tissue sealants and tissue adhesive market.
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